ICD code definitions

CPT® Code 95921: Cardiovagal Autonomic Function Testing

October 23, 2026
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3 min read
CPT® Code 95921

CPT® Code 95921 is used to report autonomic function testing of cardiovagal innervation, specifically assessment of parasympathetic function. The service evaluates cardiovascular responses controlled by the autonomic nervous system.

This testing may be performed as part of an autonomic nervous system evaluation when a clinician needs to assess cardiovagal function.

Key Facts About CPT® 95921

  • Service type: Autonomic nervous system testing ‍
  • Test: Cardiovagal function testing ‍
  • System assessed: Parasympathetic/autonomic cardiovascular function ‍
  • Purpose: Evaluate cardiovagal autonomic function ‍
  • Common specialties: Neurology, cardiology, autonomic medicine ‍
  • Provider type: Physician or qualified healthcare professional

Common clinical uses:

  • Evaluation of suspected autonomic dysfunction
  • Assessment of parasympathetic cardiovascular function
  • Evaluation of autonomic neuropathy
  • Assessment of abnormal cardiovascular autonomic responses

When to Use CPT® 95921

CPT 95921 may be reported when appropriate autonomic function testing is performed to evaluate cardiovagal innervation and parasympathetic function.

Examples:
  • A patient is evaluated for symptoms suggesting autonomic dysfunction
  • Cardiovascular autonomic testing is performed to assess parasympathetic responses
  • Testing is used as part of an evaluation for suspected autonomic neuropathy

The specific testing performed should meet applicable CPT and payer requirements.

Documentation Requirements

Documentation supporting CPT 95921 should include:

  • Patient identifiers and date of service
  • Relevant symptoms, diagnoses, or clinical indications
  • Reason autonomic testing was medically necessary
  • Testing performed to evaluate cardiovagal function
  • Test findings and measurements
  • Interpretation of results, when applicable
  • Provider authentication

The record should clearly connect the testing to the patient's clinical evaluation and document the autonomic function assessed.

Reimbursement and Coding Considerations

  • CPT 95921 reports testing of cardiovagal innervation
  • It is generally reported as part of autonomic nervous system testing when applicable
  • Other autonomic testing codes may apply depending on the components performed
  • Medical necessity and coverage requirements vary by payer
  • Practices should verify current CPT and payer-specific coding requirements before submitting claims

Accurate documentation of the autonomic testing performed and the clinical indication helps support appropriate coding and reimbursement.

How OptiMantra Supports Autonomic Testing Documentation

OptiMantra helps practices document symptoms, diagnostic findings, testing, diagnoses, and treatment plans within the patient's medical record.

With OptiMantra, providers can:

  • Document indications for autonomic function testing
  • Record relevant symptoms and clinical findings
  • Document cardiovagal testing results
  • Use customizable chart templates for consistent documentation
  • Link test findings to diagnoses and treatment plans
  • Maintain organized longitudinal patient records

Try OptiMantra for free here!

Disclaimer: CPT® codes are maintained by the American Medical Association. This guide is for informational purposes only and does not replace official coding guidelines or payer policies.

Jessica Castro
Jessica Castro

Jessica is a Massachusetts-based LPN with 13+ years of experience in patient care, healthcare technology, and education. As the Implementation and Customer Success Manager at OptiMantra, she helps providers optimize EMR solutions for better workflows and patient outcomes. With a Bachelor's in Community Health and a Master's in Healthcare Innovation in progress, she is passionate about leveraging technology to improve care delivery. Through her writing, she shares insights on healthcare best practices, EHR optimization, and patient advocacy to support providers in delivering exceptional care.