ICD code definitions

CPT® Code 87430: Streptococcus Group A Antigen Detection

August 28, 2026
3 min read
CPT® Code 87430

CPT® Code 87430 is used to report immunoassay-based antigen detection for Group A Streptococcus, commonly known as a rapid strep test. The test detects Group A Streptococcus antigens from a patient specimen and is frequently used when evaluating symptoms suggestive of streptococcal pharyngitis (strep throat).

Rapid Group A Streptococcus testing can provide results during the patient's visit and help clinicians determine whether additional evaluation or treatment may be appropriate based on the patient's clinical presentation and applicable guidelines.

Key Facts About CPT® 87430

  • Service type: Laboratory infectious disease test
  • Test: Group A Streptococcus antigen detection
  • Method: Immunoassay
  • Specimen: Typically a throat specimen
  • Test purpose: Evaluate for Group A Streptococcus infection
  • Provider type: Physicians, laboratories, and qualified healthcare professionals

Common clinical indications:

  • Sore throat
  • Suspected streptococcal pharyngitis
  • Fever with pharyngeal symptoms
  • Tonsillar inflammation or exudate
  • Exposure to confirmed Group A Streptococcus infection

When to Use CPT® 87430

CPT 87430 may be appropriate when:

  • A provider performs a Group A Streptococcus antigen immunoassay
  • The patient has clinical findings that warrant testing for strep throat
  • A rapid antigen test is performed during an office or outpatient visit
  • The result is used alongside the patient's clinical findings to guide further evaluation

Examples:

  • Testing a patient with a sore throat and fever for Group A Streptococcus
  • Performing a rapid strep test when clinical findings suggest streptococcal pharyngitis
  • Evaluating a patient after exposure to someone with confirmed strep infection

A negative rapid antigen test may require additional testing in certain patient populations and clinical circumstances, according to applicable guidelines.

Documentation Requirements

To support CPT 87430 billing, documentation should include:

  • Patient identifiers and date of service
  • Clinical indication for testing
  • Relevant symptoms and physical examination findings
  • Specimen collected
  • Group A Streptococcus antigen test performed
  • Test result and date reported
  • Ordering or performing provider information

Documentation should establish why the test was medically necessary and support the interpretation and follow-up of the result.

Reimbursement and Coding Considerations

  • CPT 87430 reports Group A Streptococcus antigen detection by immunoassay
  • Diagnosis coding should support the patient's symptoms, suspected infection, or other medical necessity
  • A rapid antigen test should be distinguished from Group A Streptococcus culture or molecular testing, which may use different CPT codes
  • Follow-up testing after a negative rapid antigen result may be appropriate depending on the patient's age, clinical presentation, and applicable guidelines
  • Coverage and reimbursement vary by payer and clinical indication

Always verify current CPT guidance, applicable clinical recommendations, and payer-specific laboratory billing requirements before submitting claims.

How OptiMantra Supports Strep Testing

OptiMantra's integrated EMR and practice management platform helps streamline documentation and billing for CPT 87430.

With OptiMantra, providers can:

  • Order Group A Streptococcus testing within the patient chart
  • Document symptoms, examination findings, and clinical indications
  • Record rapid strep test results in the patient's medical record
  • Link laboratory findings to diagnoses and treatment plans
  • Document follow-up recommendations based on test results
  • Maintain organized laboratory documentation that supports billing compliance and audit preparedness

By centralizing point-of-care testing and clinical documentation, OptiMantra helps practices maintain efficient workflows and comprehensive patient records.

Try OptiMantra for free here!

Disclaimer: CPT® codes are maintained by the American Medical Association. This guide is for informational purposes only and does not replace official coding guidelines or payer policies.

Jessica Castro
Jessica Castro

Jessica is a Massachusetts-based LPN with 13+ years of experience in patient care, healthcare technology, and education. As the Implementation and Customer Success Manager at OptiMantra, she helps providers optimize EMR solutions for better workflows and patient outcomes. With a Bachelor's in Community Health and a Master's in Healthcare Innovation in progress, she is passionate about leveraging technology to improve care delivery. Through her writing, she shares insights on healthcare best practices, EHR optimization, and patient advocacy to support providers in delivering exceptional care.