CPT® code 82627 is used to report a laboratory test measuring vitamin B12 (cobalamin) levels in the blood. Vitamin B12 is essential for red blood cell production, neurological function, and DNA synthesis. Testing is commonly performed to diagnose deficiencies, monitor supplementation, or evaluate certain hematologic and neurological conditions.
When to Use CPT® Code 82627
- When evaluating patients for vitamin B12 deficiency due to dietary insufficiency, malabsorption, or medication effects.
- To investigate anemia, fatigue, neuropathy, or cognitive changes.
- To monitor response to vitamin B12 supplementation or injections.
- Often ordered alongside folate or methylmalonic acid (MMA) tests for a comprehensive assessment.
Billing Requirements
- Report per test performed.
- Documentation should include the medical reason for testing, relevant patient history, and any supplementation plan.
- May be billed in conjunction with other lab tests but must be separately documented.
- Ensure proper ICD-10 codes are applied to support medical necessity.
Common Clinical Scenarios
- A primary care provider orders a B12 test for a patient presenting with fatigue and neurological symptoms.
- An integrative clinic monitors a patient receiving vitamin B12 injections for deficiency management.
- A gastroenterologist checks B12 levels in a patient with malabsorption due to Crohn’s disease or bariatric surgery.
Streamline Vitamin B12 Testing with OptiMantra
Accurate documentation and billing for CPT® 82627 are essential for compliance and proper reimbursement. OptiMantra’s EMR and practice management system allows providers to order lab tests, track results, and integrate findings directly into patient records. For primary care, integrative, and specialty clinics, OptiMantra simplifies lab workflows, reduces administrative tasks, and helps providers focus on patient care while ensuring accurate claims.
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