ICD code definitions

CPT® Code 81003: Urinalysis, Automated with Microscopy

September 19, 2025
3 min read
CPT® Code 81003

CPT® code 81003 is used to report an automated urinalysis with microscopy performed for diagnostic evaluation of urine samples. This test assesses multiple urine components, including cells, casts, crystals, and other microscopic elements, which can help detect urinary tract infections, kidney disease, or metabolic disorders.

When to Use CPT® Code 81003

  • When evaluating patients for urinary tract infections, hematuria, proteinuria, or kidney dysfunction.
  • For patients presenting with abnormal urinalysis dipstick results, requiring microscopic confirmation.
  • To monitor known urinary conditions or response to treatment.
  • Often ordered as part of a routine health exam or diagnostic workup in primary care, integrative, or specialty clinics.

Billing Requirements

  • Report per test performed.
  • Documentation should include clinical indication, specimen collection date, and method.
  • May be performed alongside other lab tests, each billed separately.
  • Ensure proper ICD-10 codes reflecting medical necessity are included for payer compliance.

Common Clinical Scenarios

  • A primary care provider orders automated urinalysis with microscopy for a patient with recurrent urinary tract infections.
  • A nephrologist monitors protein levels and casts in a patient with chronic kidney disease.
  • An integrative clinic screens for metabolic disorders in patients with abnormal lab results or risk factors.

Streamline Urinalysis Testing with OptiMantra

Accurate documentation and billing for CPT® 81003 are essential for compliance and proper reimbursement. OptiMantra’s EMR and practice management platform allows providers to order lab tests, track microscopic findings, and integrate results into patient records. For primary care, specialty, and integrative practices, OptiMantra simplifies lab workflows, reduces administrative tasks, and ensures providers can focus on delivering high-quality patient care.

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Jessica Castro
Jessica Castro

Jessica is a Massachusetts-based LPN with 13+ years of experience in patient care, healthcare technology, and education. As the Implementation and Customer Success Manager at OptiMantra, she helps providers optimize EMR solutions for better workflows and patient outcomes. With a Bachelor's in Community Health and a Master's in Healthcare Innovation in progress, she is passionate about leveraging technology to improve care delivery. Through her writing, she shares insights on healthcare best practices, EHR optimization, and patient advocacy to support providers in delivering exceptional care.