CPT® Code 82274 is used to report a qualitative fecal immunochemical test (FIT) that detects occult (hidden) blood in stool by measuring human hemoglobin using an immunoassay (IA). This noninvasive laboratory test is commonly used for colorectal cancer screening and for evaluating patients with suspected lower gastrointestinal bleeding.
Unlike traditional guaiac-based fecal occult blood tests, the FIT is specific for human hemoglobin and does not require dietary restrictions prior to testing.
This code represents the laboratory test only, not specimen collection or interpretation services, which may be reported separately when appropriate.
Key Facts About CPT® 82274
- Service type: Laboratory test
- Test: Fecal immunochemical test (FIT) for occult blood
- Method: Immunoassay (IA), qualitative
- Specimen type: Feces (stool)
- Test purpose: Detect occult blood in stool
- Provider type: Laboratories, physicians, and qualified healthcare professionals
Common clinical indications:
- Colorectal cancer screening
- Evaluation of occult gastrointestinal bleeding
- Investigation of unexplained iron deficiency anemia
- Assessment of lower gastrointestinal symptoms
- Follow-up evaluation when clinically indicated
When to Use CPT® 82274
CPT 82274 is appropriate when:
- Performing a qualitative fecal immunochemical test for occult blood
- Screening average-risk adults for colorectal cancer according to clinical guidelines
- Evaluating patients with suspected lower gastrointestinal bleeding
- Investigating unexplained iron deficiency anemia or positive gastrointestinal symptoms
Examples:
- Annual colorectal cancer screening using a FIT test
- Evaluating a patient with unexplained iron deficiency anemia
- Assessing occult gastrointestinal bleeding in a patient with chronic fatigue
- Performing stool testing as part of a diagnostic gastrointestinal workup
Documentation Requirements
To support CPT 82274 billing, documentation should include:
- Patient identifiers and date of service
- Clinical indication for testing or preventive screening
- Stool specimen documentation
- Test performed (fecal hemoglobin immunoassay, qualitative)
- Test results and date reported
- Ordering provider information
Complete documentation supports medical necessity and accurate laboratory billing.
Reimbursement and Coding Considerations
- CPT 82274 is commonly covered for colorectal cancer screening in eligible patients according to payer and preventive care guidelines
- Diagnosis coding should support either preventive screening or the evaluation of gastrointestinal symptoms when applicable
- This code applies to immunoassay-based fecal hemoglobin testing and should not be used for guaiac-based fecal occult blood testing
- Frequency limitations for preventive screening may apply depending on payer policy and patient eligibility
- Coverage varies among commercial insurers and government payers
Always verify payer-specific preventive screening and laboratory billing requirements before submitting claims.
How OptiMantra Supports Preventive Screening and Laboratory Testing
OptiMantra’s integrated EMR and practice management system streamlines documentation and billing for CPT 82274:
With OptiMantra, providers can:
- Order FIT testing within the patient chart
- Track preventive screening results and patient screening history over time
- Link laboratory findings to diagnoses, preventive care plans, and follow-up recommendations
- Maintain organized clinical and laboratory documentation that supports billing compliance and audit preparedness
- Centralize laboratory workflows and preventive care management within one platform
By integrating preventive screening and laboratory documentation, OptiMantra helps practices improve efficiency, ensure compliance, and support timely patient care.
Try OptiMantra for free here!
Disclaimer: CPT® codes are maintained by the American Medical Association. This guide is for informational purposes only and does not replace official coding guidelines or payer policies.
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