ICD code definitions

CPT® Code 86141: Hepatitis B Surface Antibody Test

September 30, 2025
3 min read
CPT® Code 86141

Definition:
CPT® 86141 describes a laboratory test used to detect hepatitis B surface antibodies (anti-HBs) in the blood. This test determines immune status following vaccination or prior exposure to hepatitis B and helps guide clinical decisions for vaccination or further evaluation.

When to Use:

  • To assess immunity after hepatitis B vaccination or potential exposure.
  • For patients at risk of hepatitis B infection, including healthcare workers or individuals with high-risk behaviors.
  • As part of a pre-vaccination or post-exposure screening protocol.

Documentation Requirements:
To support billing for CPT® 86141, clinicians should document:

  • Medical necessity, including vaccination history or potential exposure.
  • Relevant patient risk factors and clinical indications.
  • Any follow-up plans based on antibody results, including additional vaccination or monitoring.

Key Notes:

  • CPT® 86141 specifically tests for hepatitis B surface antibodies; other hepatitis B markers are billed separately.
  • Accurate documentation ensures payer compliance and supports proper reimbursement.

How OptiMantra Supports 86141:
OptiMantra’s EMR and practice management platform enables providers to order hepatitis B antibody tests directly from the chart, track clinical indications, and automatically integrate results into patient records. This streamlines documentation, supports clinical decision-making, and ensures clean, compliant claims for faster reimbursement.

Jessica Castro
Jessica Castro

Jessica is a Massachusetts-based LPN with 13+ years of experience in patient care, healthcare technology, and education. As the Implementation and Customer Success Manager at OptiMantra, she helps providers optimize EMR solutions for better workflows and patient outcomes. With a Bachelor's in Community Health and a Master's in Healthcare Innovation in progress, she is passionate about leveraging technology to improve care delivery. Through her writing, she shares insights on healthcare best practices, EHR optimization, and patient advocacy to support providers in delivering exceptional care.