ICD code definitions

CPT® Code 82670: Estradiol Test

September 11, 2025
3 min read
CPT® Code 82670

CPT® code 82670 is used to report a laboratory test measuring estradiol (E2) levels in the blood. Estradiol is one of the primary forms of estrogen and plays a critical role in reproductive health, endocrine function, and hormone balance. This test is widely used in evaluating fertility, menstrual irregularities, menopause, and certain endocrine disorders.

When to Use CPT® Code 82670

  • When ordering a blood test to measure serum estradiol levels.
  • For patients undergoing fertility evaluation or monitoring assisted reproductive therapy.
  • For assessing menopausal status or abnormal menstrual cycles.
  • When evaluating hormone-related conditions such as gynecomastia, hypogonadism, or estrogen-secreting tumors.

Billing Requirements

  • Report per test performed.
  • Documentation should include the clinical reason for ordering estradiol testing (e.g., infertility workup, hormone imbalance).
  • Some payers may require specific ICD-10 codes to establish medical necessity.
  • Not typically billed with other hormone tests unless clinically justified.

Common Clinical Scenarios

  • A fertility clinic orders an estradiol test to monitor ovarian stimulation in a patient undergoing IVF.
  • A gynecologist evaluates a patient with irregular menstrual cycles and uses estradiol levels to guide diagnosis.
  • An endocrinologist orders the test to assess a male patient with suspected hypogonadism.

Streamline Hormone Testing Documentation with OptiMantra

Accurate billing and documentation for lab services like CPT® 82670 are essential for both compliance and reimbursement. OptiMantra’s EMR and practice management system helps providers seamlessly order lab tests, track results, and link diagnostic codes for clean claims. Whether you manage a fertility clinic, women’s health practice, or integrative wellness center, OptiMantra makes hormone testing workflows more efficient—so you can focus on delivering excellent patient care.

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Jessica Castro
Jessica Castro

Jessica is a Massachusetts-based LPN with 13+ years of experience in patient care, healthcare technology, and education. As the Implementation and Customer Success Manager at OptiMantra, she helps providers optimize EMR solutions for better workflows and patient outcomes. With a Bachelor's in Community Health and a Master's in Healthcare Innovation in progress, she is passionate about leveraging technology to improve care delivery. Through her writing, she shares insights on healthcare best practices, EHR optimization, and patient advocacy to support providers in delivering exceptional care.