ICD code definitions

CPT® Code 80061: Lipid Panel

July 25, 2025
3 min read
CPT® Code 80061

CPT® code 80061 is used to report a lipid panel laboratory test, which measures the levels of cholesterol and triglycerides in the blood. This test is commonly performed in outpatient clinics, preventive medicine, cardiology, and integrative wellness practices to assess cardiovascular risk and guide treatment decisions.

What is CPT Code 80061?

CPT 80061 covers a group of tests that analyze blood lipids, including:

  • Total cholesterol
  • High-density lipoprotein (HDL) cholesterol
  • Low-density lipoprotein (LDL) cholesterol
  • Triglycerides

This panel provides essential information to evaluate a patient’s risk for heart disease, stroke, and other cardiovascular conditions. It is widely used for routine screening, diagnosis, and monitoring of lipid disorders.

When to Use CPT Code 80061

Use CPT 80061 when ordering a lipid panel laboratory test on a patient to assess lipid levels and cardiovascular risk. Typical clinical scenarios include:

  • Preventive health screenings for adults, especially those with risk factors like obesity, hypertension, or diabetes
  • Monitoring lipid levels in patients on cholesterol-lowering medications
  • Evaluating unexplained chest pain or other cardiovascular symptoms
  • Assessing risk prior to initiating or adjusting therapy

Documentation should include:

  • Indication for the test (e.g., routine screening, hyperlipidemia management)
  • Relevant patient history and risk factors
  • Test results and interpretation
  • Follow-up plan based on lipid profile findings

Coding Considerations

  • CPT 80061 is a panel code and should not be reported in conjunction with the individual component tests it includes.
  • The test is generally performed on serum or plasma specimens.
  • Some payers may require fasting before sample collection for accurate triglyceride measurement.
  • The lipid panel may be part of broader metabolic panels, but billing guidelines typically require separate reporting only when medically necessary.

CPT 80061 and Cardiovascular Risk Management

The lipid panel is a cornerstone of cardiovascular preventive care. Regular testing helps clinicians identify patients at increased risk and tailor lifestyle interventions or pharmacologic treatment accordingly.

Proper coding and documentation are critical to ensure compliance and reimbursement, especially as lipid screening becomes more common in value-based care models.

Streamline Lab Test Management with OptiMantra

OptiMantra helps practices efficiently manage lab orders, results, and billing for tests like the lipid panel by offering:

  • Integrated lab ordering and tracking within patient charts
  • Coding with CPT 80061 linked to corresponding ICD-10 diagnosis codes
  • Seamless incorporation of lab results into clinical notes and care plans
  • Simplified claims submission and reimbursement tracking

With OptiMantra, providers can optimize cardiovascular risk screening workflows, delivering better patient care while maximizing operational efficiency and revenue.

Try OptiMantra for free here!

Jessica Castro
Jessica Castro

Jessica is a Massachusetts-based LPN with 13+ years of experience in patient care, healthcare technology, and education. As the Implementation and Customer Success Manager at OptiMantra, she helps providers optimize EMR solutions for better workflows and patient outcomes. With a Bachelor's in Community Health and a Master's in Healthcare Innovation in progress, she is passionate about leveraging technology to improve care delivery. Through her writing, she shares insights on healthcare best practices, EHR optimization, and patient advocacy to support providers in delivering exceptional care.

Related articles