ICD code definitions

CPT® Code 87426: COVID-19 Antigen Test, Swab

December 4, 2025
3 min read
CPT® Code 87426

Overview
CPT® Code 87426 is used to report rapid antigen testing for SARS-CoV-2 (COVID-19) performed using a swab specimen. These tests detect viral proteins and are often used for point-of-care or rapid diagnostic testing. Unlike molecular PCR tests, antigen tests provide faster results but may be less sensitive, particularly in asymptomatic patients.

The code reflects the laboratory or point-of-care test itself. Interpretation and patient counseling are reported separately if provided.

Key Facts About CPT® 87426

  • Service type: Clinical laboratory or point-of-care test
  • Provider type: Physicians, qualified healthcare professionals, laboratories, or authorized testing sites
  • Medical services included: Detection of SARS-CoV-2 antigen using a swab specimen
  • Specimen type: Nasal, nasopharyngeal, or other FDA-approved swabs
  • Common clinical indications:
    • Symptomatic patients suspected of COVID-19
    • Exposure or surveillance testing
    • Pre-procedural screening
    • Outbreak or contact tracing scenarios

When to Use CPT® 87426

CPT 87426 is appropriate when:

  • A patient requires a rapid COVID-19 antigen test using a swab
  • Testing is medically necessary for diagnosis, surveillance, or exposure evaluation
  • Results are used to guide infection control measures, isolation, or treatment decisions

Examples:

  • Symptomatic patient presents with fever and cough; rapid antigen testing is performed
  • Preoperative COVID-19 screening for elective procedures
  • Testing for exposure in a workplace or school outbreak

Documentation Requirements

To properly support CPT 87426 billing, documentation should include:

  • Patient identifiers and date of testing
  • Specimen type and collection method
  • Indication for testing (symptomatic, exposure, surveillance)
  • Test result and interpretation
  • Any follow-up recommendations, isolation instructions, or treatment guidance

Accurate documentation ensures proper reimbursement, compliance, and record integration.

Reimbursement and Coding Considerations

  • CPT 87426 is covered by most commercial insurers, Medicaid, and Medicare when medically necessary
  • Interpretation or counseling must be billed separately
  • Some payers may require additional modifiers for outpatient vs. point-of-care settings
  • Always verify payer-specific policies, especially regarding rapid COVID-19 testing and reimbursement

How OptiMantra Supports COVID-19 Antigen Testing

OptiMantra’s integrated EMR and practice management system simplifies documentation, tracking, and billing for CPT 87426:

With OptiMantra, providers can:

  • Record swab collection, patient information, and test results directly in the EMR
  • Track trends, positive/negative rates, and patient follow-up over time
  • Document patient counseling, isolation instructions, and infection control measures
  • Generate clean, audit-ready billing codes for rapid claims submission
  • Integrate COVID-19 testing with broader care plans and reporting requirements

By centralizing testing workflows, OptiMantra ensures accurate records, streamlined operations, and proper reimbursement for COVID-19 antigen testing.

Try OptiMantra for free here!

Jessica Castro
Jessica Castro

Jessica is a Massachusetts-based LPN with 13+ years of experience in patient care, healthcare technology, and education. As the Implementation and Customer Success Manager at OptiMantra, she helps providers optimize EMR solutions for better workflows and patient outcomes. With a Bachelor's in Community Health and a Master's in Healthcare Innovation in progress, she is passionate about leveraging technology to improve care delivery. Through her writing, she shares insights on healthcare best practices, EHR optimization, and patient advocacy to support providers in delivering exceptional care.